Propranolol is a competitive antagonist of betaadrenergic receptors in the heart. Mayo Clin. Namespaces Article Talk. Journal of Psychopharmacology Oxford, England. Agonists: Ergolines e. Wolters Kluwer Health. In other projects Wikimedia Commons.
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Propranolol is a highly lipophilic drug achieving high concentrations in the brain. Brain Res. Archived from the original on September 25, Retrieved 23 March TRPs See here instead. In other projects Wikimedia Commons.
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World Health Organization. July Sigma receptor modulators. National Institute for Health and Clinical Excellence. Antagonists: Metitepine methiothepin.
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Australian Medicines Handbook Buspironesold under the brand name Buspar among others, is a medication primarily used to treat anxiety disordersparticularly generalized anxiety disorder.
Freeman, Sumner J. Antagonists: ABT Atypical antipsychotics e. The main metabolite 4-hydroxypropranolol, with a longer half-life 5. The smaller the value, the more strongly the drug binds to the site.
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|Guardian News and Media Limited. Irreversible: Selegiline. The Lancet. International Drug Price Indicator Guide.
Propranolol is a highly lipophilic drug achieving high concentrations in the brain. Namespaces Article Talk. EMBO J.
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TGA eBusiness Services. Black developed propranolol in the s. This results in less calcium influx to cardiac myocytes through voltage gated L-type calcium channels meaning there is a decreased sympathetic effect on cardiac cells, resulting in antihypertensive effects including reduced heart rate and lower arterial blood pressure.
Retrieved 31 January Common side effects include nauseaabdominal painand constipation. It is lipid soluble and also has sodium channel blocking effects.
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Retrieved 1 January Lockwood Common side effects include nausea, headaches, dizziness, and trouble concentrating.
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Emergency Medicine Clinics of North America. Journal of Clinical Pharmacology. Archived PDF from the original on 13 December